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The University of Texas at Arlington
Graduate Catalog 2002-2004


Program in Biomedical Engineering

www.uta.edu/biomed_eng
Admission Requirements | Continuation | Degree Requirements | Courses | Combined Degree Plan

Area of Study and Degrees

Biomedical Engineering

M.S., Ph.D.

Biomedical Engineering

Industrial Internship

Master's Degree Plans

Thesis and Non-Thesis

Director

Khosrow Behbehani, Interim Director

Graduate Advisor

Charles C.J. Chuong

220 Engineering Laboratory, 817-272-2249

Graduate Faculty

Professors

Behbehani, Chuong

Associate Professors

Liu, Tang

Assistant Professor

Nelson

Adjunct Faculty

(U.T. Southwestern and U.T. Arlington)

Ahrens, Antich, Bertocci, Blomqvist,

Cadeddu, Cameron, Cook, Eberhart

Elsenbaumer, Finnegan, Franklin, Gall,

Garner, Giller, Hagler, Horton, Jessen,

Johnson, Kondraske, Kulkarni, Lucas,

Manry, Markin, Mason, McColl,

Nomura, Ordway, Peshock, Peterson,

Petroll, Prager, Srebro, Timmons,

Triano, Wallace, Wang, Williams

Objectives

The Biomedical Engineering Program is jointly offered by The University of Texas at Arlington and The University of Texas Southwestern Medical Center at Dallas (U.T. Southwestern). Research and teaching efforts of various departments in the biological, engineering, mathematical, physical, and medical sciences of both institutions are coordinated through the Committee on Graduate Studies in Biomedical Engineering. The goal of the program is to prepare students as biomedical engineers for productive research, development, and teaching careers in academic, industrial, hospital, or governmental positions.

The program includes coursework and research in artificial organs, biosensors, physiological control systems, biomedical signal processing, medical image processing, biomedical instrumentation, rehabilitation, orthopedics, biomechanics, biomaterials and tissue engineering, cell and molecular engineering, genomics, recombinant DNA technology, and neurosciences. Specifically, during the first year of their studies, students in the master's and doctoral programs must select one of the concentration tracks in Biomedical Engineering: 1) Bioinstrumentation, 2) Biomaterials/Tissue Engineering, 3) Biomechanics, 4) Medical Imaging, and 5) Molecular and Computational Biomedical Engineering. An advisor is available to advise students on the relevant courses and the research opportunities in each track.

A one-semester internship in Dallas/Fort Worth industry prepares students for careers in the biomedical engineering industry.

The master's program is based upon graduate level work in one of the engineering disciplines, biomedical engineering, and life sciences.

The doctoral program is based upon graduate level work in one of the engineering disciplines and extensive graduate training in the life sciences and related physical sciences. The program is aimed at the development of professional biomedical engineers capable of independent research.

Admission

Application for admission should be made at either U.T. Arlington or U.T. Southwestern. Normally, the institution through which the student applies and is admitted is the student's home institution. Admission in the other institution is initiated during the student's first semester.

In addition to admission requirements of the Graduate School, the bachelor's degree held by applicants to the program may be in engineering, biological, physical, or mathematical sciences. The UTA Biomedical Engineering Program uses the following guidelines in the admission review process:

Unconditional Admission

Master's Program

  1. Minimum undergraduate GPA of 3.0 in the last 60 hours of undergraduate work in an engineering discipline as calculated by the Graduate School.
  2. GREcombined verbal and quantitative score greater than 1,100 and a verbal score of 400 or better.
  3. Three favorable letters of recommendation.
  4. A TOEFL score of 575 or better for international students whose native language is not English.

Doctoral Program

  1. Minimum GPA of 3.4 in the last 60 hours taken in the major field of study of engineering or physical sciences as calculated by the Graduate School.
  2. 2. GREcombined verbal and quantitative score greater than 1,175 and a verbal score of 400 or better.
  3. 3. Three favorable letters of recommendation.
  4. 4. A TOEFL score of 575 or better for international students whose native language is not English.

Probationary Admission

Master's Program

1. If the applicant meets any two of the above items 1, 2, and 3.

2. A TOEFL score of 575 or better for international students whose native language is not English.

Doctoral Program

1. If an applicant meets any two of the above items 1, 2, and 3.

2. A TOEFL score of 575 or better for international students whose native language is not English.

Provisional Admission

An applicant unable to supply all required documents prior to the admission deadline, but who otherwise appears to meet admission requirements may be granted provisional admission.

Deferral

If an applicant does not present adequate evidence of meeting admission requirements, the admission decision may be deferred until records are complete.

Denial

A candidate may be denied admission if he/she has less than satisfactory performance in two out of the three admission criteria, excluding TOEFL.

Fellowship

No additional requirements besides what is published by the Graduate School.

Continuation

The Biomedical Engineering Graduate Program has established certain policies to fulfill its responsibility to graduate highly qualified professional engineers. In addition to the requirements of the Graduate School listed in this catalog under Advanced Degrees and Requirements, each biomedical engineering graduate student who wants to continue in the program must:

1. Maintain at least a B (3.0) overall GPA in all coursework, and

2. Demonstrate suitability for professional engineering practice.

At such time as questions are raised by biomedical engineering graduate faculty regarding either of the above, the student will be notified and will be provided the opportunity to respond to the Committee on Graduate Studies in Biomedical Engineering. The Committee on Graduate Studies will review the student's performance and make a recommendation concerning the student's eligibility to continue in the program. Appeal of a decision on continuation may be made through normal procedures outlined in the section of this catalog entitled "Grievances Other than Grades."

Degree Requirements

Master of Science Degree Plans

Students in the Thesis Degree plan must take a minimum of 38 credit hours, and students in the Non-Thesis Degree plan must take a minimum of 39 credit hours as specified below.

Required Biomedical Engineering: Bioinstrumentation (BME 5344); Laboratory Principles (BME 5382); BME Seminar (BME 5201).

Elective Biomedical Engineering: Four courses from: Biological Materials, Mechanics, and Processes (BME 5335); Finite Element Applications in Biomechanics (BME 5340); Biosensors and Applications (BME 5345); Modeling and Control of Biological Systems (BME 5350); Digital Control of Biomedical Systems (BME 5351); Digital Processing of Biological Signals (BME 5352); Design and Application of Artificial Organs (BME 5360); Thermoregulation and Bioheat Transfer (BME 5362); Biomaterials and Blood Compatibility (BME 5361); Introduction to Orthopedic Mechanics (BME 5331D); Orthopedic Biomaterials (BME 5332D); Tissue Engineering (BME 5364); Tissue Engineering Laboratory (BME 5365); Biomaterial-Living System Interactions (BME 5370).

Other Engineering: Two courses from other engineering departments, with the approval of the Graduate Advisor.

Life Sciences: Human Physiology (BME 5309D); Human Anatomy (BME 5307D).

Thesis Plan: Directed Research in Biomedical Engineering (BME 5391), re-enroll as needed; Thesis (BME 5698) at the semester in which the student expects to submit and defend the thesis.

Non-thesis Plan: Master's Comprehensive Examination (BME 5193); Research Project (BME 5390), re-enroll as needed; and one 3-hour graduate level course from Life Science, Engineering, or BME.

Doctor of Philosophy Degree Plan

The Ph.D. degree program consists of a minimum of 58 credit hours beyond the bachelor's degree level (exclusive of required Ph.D. exams) and includes the courses as specified below. Course requirements differ for the Molecular and Computational Biomedical Engineering track. See track advisor for details.

Required Biomedical Engineering: Bioinstrumentation I (BME 5344); Laboratory Principles (BME 5382); BME Seminar (BME 5201); Ph.D. Seminar in BME (BME 6103) for at least two semesters.

Elective Biomedical Engineering: Six courses from: Biological Materials, Mechanics, and Processes (BME 5335); Finite Element Applications in Biomechanics (BME 5340); Biosensors and Applications (BME 5345); Modeling and Control of Biological Systems (BME 5350); Digital Control of Biomedical Systems (BME 5351); Digital Processing of Biological Signals (BME 5352); Design and Application of Artificial Organs (BME 5360); Thermoregulation and Bioheat Transfer (BME 5362); Biomaterials and Blood Compatibility (BME 5361); Introduction to Orthopedic Mechanics (BME 5331D); Orthopedic Biomaterials (BME 5332D); Tissue Engineering (BME 5364); Tissue Engineering Laboratory (BME 5365); Biomaterial-Living System Interactions (BME 5370).

Other Engineering: Three courses from other engineering departments (approval from the Graduate Advisor).

Life Sciences: Human Physiology (BME 5309D); Human Anatomy (BME 5307D); Human Anatomy Dissection Lab (BME 5308D); Biochemistry (BME 5306D) or [General Biochemistry I (CHEM 4311) and General Biochemistry II (CHEM 4312)]. One additional life science course is required unless six hours are taken in Physiology or Biochemistry (consult with the Graduate Advisor).

Mathematics, Statistics, Computer and Physical Sciences: Choose two relevant graduate level courses (approval from the Graduate Advisor).

Ph.D. Examinations and Dissertation: All doctoral students must satisfactorily complete the following exams: Doctoral Diagnostic Examination (BME 6194), Doctoral Comprehensive Examination (BME 6195), and Dissertation (BME 6999) at the semester in which the student expects to submit and defend the dissertation.

Although qualified applicants may be accepted into the Ph.D. program without earning the Master of Science in biomedical engineering, all students must satisfactorily pass the Doctoral Diagnostic Examination (BME 6194). This examination will cover all relevant coursework taken by the student. The examination may be written, oral, or both and consists of a timed, written analysis of a major problem in the student's general area of research of interest, followed by an oral examination covering the same material. Elements of engineering, physical and biological science, mathematics, computer science and statistics may be included in this examination.

For additional information, applicants and students should contact the BME Graduate Advisor for a copy of the "Information Brochure" for related and amplified information about the graduate program. The information can also be found at http://www.uta.edu/biomed_eng/.

Note: In degree plan descriptions, course numbers followed by a D are offered at U.T. Southwestern.

The grade of R (research in progress) is a permanent grade; it cannot be changed by completing course requirements in a later semester. To receive credit for an R-graded course, the student must continue to enroll in the course until a passing grade is received.

An incomplete grade (the grade of X) cannot be given in a course that is graded R, nor can the grade of R be given in a course that is graded X. To receive credit for a course in which the student earned an X, the student must complete the course requirements. A grade of X cannot be changed by enrolling again in the course in which an X was earned. At the discretion of the instructor, a final grade can be assigned through a change of grade form.

Three-hour thesis courses and three- and six-hour dissertation courses are graded R/F/W only (except social work thesis courses). The grade of P (required for degree completion for students enrolled in thesis or dissertation programs) can be earned only in six- or nine-hour thesis courses and nine-hour dissertation courses. In the course listings below, R-graded courses are designated either "Graded P/F/R" or "Graded R." Occasionally, the valid grades for a course change. Students should consult the appropriate Graduate Advisor or instructor for valid grade information for particular courses. (See also the sections titled "R" Grade, Credit for Research, Internship, Thesis or Dissertation Courses and Incomplete Grade in this catalog.)

Biomedical Engineering (BME)

Course fee information is published in the online Student Schedule of Classes at www.uta.edu/schedule. Please refer to this Web site for a detailed listing of specific course fees.

5102. INTRODUCTION TO RESEARCH IN BIOMEDICAL ENGINEERING (1-0). Overview of necessary research tools, including methods of scientific research, formulation of hypotheses, design of experiments, data analysis, biostatistics, library database research, technical writing, and technical paper presentation. Graded P/F only.

5201. SEMINAR IN BIOMEDICAL ENGINEERING (2-0). University and guest lecturers speak on topics of current interest in the field of biomedical engineering.

5191, 5291, 5391. DIRECTED RESEARCH IN BIOMEDICAL ENGINEERING. Student participates in a research project under the individual instruction of a faculty supervisor. Prerequisite: permission of the instructor.

5193. MASTER'S COMPREHENSIVE EXAMINATION (1-0). Individual instruction, directed study, consultation, and comprehensive examination over coursework leading to the non-thesis Master of Science degree in biomedical engineering. Graded P/F/R only. Required of all non-thesis MS students in the semester when they plan to graduate.

5300. SELECTED TOPICS IN BIOMEDICAL ENGINEERING. Material may vary from semester to semester. May be repeated for credit if different topics are covered for each registration. Prerequisite: permission of the instructor.

5335. BIOLOGICAL MATERIALS, MECHANICS AND PROCESSES (3-0). Typical functional behavior of various biological materials, flow properties of blood, bioviscoelastic fluids and solids, mass transfer in cardiovascular and pulmonary systems.

5340. FINITE ELEMENT APPLICATIONS IN BIOMECHANICS (3-0). The course describes the fundamental principles of the finite element method and various numerical modeling techniques. Topics include variational and Galerkin formulations, linear and Hermitian elements, accuracy and convergence. Applications in biological systems and to the design of prosthetic devices are emphasized. Topic areas include elasticity, heat transfer, and mass transport processes.

5344. BIOINSTRUMENTATION (3-0). Fundamental principles of bioinstrumentation, including operational amplifiers and instrumentation amplifiers; measurements of biopotentials; signals and noise in biological systems; mechanical transducers; resistive, inductive, capacitive transducers; measurement of temperature, blood pressure and flow; electrical safety.

5345. BIOSENSORS AND APPLICATIONS (3-0). Fundamental principles of biosensors, including electrochemical and fiber-optic sensors. Topics include introduction to fabrication, miniaturization techniques, and discussion of future directions, including semiconductor fabrication and nano-fabrication technology.

5350. MODELING AND CONTROL OF BIOLOGICAL SYSTEMS (3-0). Introduction to fundamental methods of modeling, analysis and control of biological systems. Linear system modeling, state space modeling, stability analysis, basic control strategies and identification techniques. Examples from cardiopulmonary, visual and motor control systems.

5351. DIGITAL CONTROL OF BIOMEDICAL SYSTEMS (3-0). Design of control strategies for microprocessor-based medical equipment. Discrete and sampled data systems, Z transform, digital control design methods, stability considerations and closed loop system response.

5352. DIGITAL PROCESSING OF BIOLOGICAL SIGNALS (3-0). Fundamental techniques for extraction of useful information from signals acquired from biological systems. Topics include time and frequency domain analysis, cross correlation, spectrum analysis, and convolution. Design of FIR and IIR filters for processing biological signals are described. Examples include cardiac, respiratory, and biomechanical movements. Prerequisite: An undergraduate engineering course in signals and systems analysis or consent of the instructor.

5360. DESIGN AND APPLICATION OF ARTIFICIAL ORGANS (3-0). Fundamental principles of fluid mechanics, mass transfer and chemical reaction in engineered biological systems. Simple solutions are developed for the design of artificial ventricular assist devices, total artificial hearts, lungs and kidneys.

5361. BIOMATERIALS AND BLOOD COMPATIBILITY (3-0). This course is an introduction to polymer structure and fabrication methods. Blood and tissue interactions with materials, and methods to improve the biocompatibility of materials are discussed.

5362. THERMOREGULATION AND BIOHEAT TRANSFER (3-0). This course focuses on the application of engineering analysis to problems in physiological and clinical heat transfer. Hyperthermia (including laser, electromagnetic, and ultrasound heating of tissue), hypothermia (including circulatory arrest and tissue freezing), and other applications are analyzed.

5364. TISSUE ENGINEERING LECTURE (3-0). Fundamentals of cell/extracellular matrix interactions in terms of cell spreading, migration, proliferation and function. Soft and hard tissue wound healing and nerve regeneration. Polymer scaffolding materials and fabrication methods. Cell-polymer interactions. In vitro and in vivo tissue culture and organ replacement.

5365. TISSUE ENGINEERING LAB (0-3). Polymer extrusion, polymer drug loading, and degradation with drug release kinetics. Each student will be given the opportunity to perform these experiments and to culture cells and test their culture for cell growth, proliferation and function under several different substrate and media conditions.

5366. PROCESS CONTROL IN BIOTECHNOLOGY (2-3). Principles and methods of measurement, data acquisition and analysis. Application of control theory in biological systems and in biotechnology processes; control of pressure, flow, temperature, and pH. Prerequisites: An undergraduate course in control theory or consent of the instructor.

5370. BIOMATERIAL-LIVING SYSTEM INTERACTIONS (3-0). This course describes current developments in molecular structure and organization at synthetic material interfaces with tissues and the subsequent influences on cells and cell membranes. It is designed to lay the groundwork for an improved understanding of events at the biomaterial-living system interface.

5382. LABORATORY PRINCIPLES (0-9). Introduction to fundamental biomedical engineering laboratory procedures including human studies and animal surgery; includes clinical laboratory
projects; data collection, analysis, and interpretation. Prerequisite: permission of the instructor.

5390. RESEARCH PROJECT (0-9). Taken by students enrolled in the non-thesis option for the MS degree. Individual instruction in research and/or instrumentation development and evaluation conducted under supervision of the instructor. A final report required. Graded P/F/R. Prerequisite: permission of the instructor.

5398, 5698 THESIS. 5398 graded R/F only; 5698 graded P/F/R. Prerequisite: graduate standing in biomedical engineering.

6103. Ph.D. SEMINAR IN BIOMEDICAL ENGINEERING (1-0). Students will be assigned to participate in the journal clubs and medical grand rounds relevant to their areas of research in Biomedical Engineering. Graded P/F only. Prerequisite: Ph.D. student status.

6194. DOCTORAL DIAGNOSTIC EXAMINATION (1-0). Individual instruction, directed study, consultation, and diagnostic examination. Graded P/F/R only. Required of all doctoral students in the semester when they take any portion of the diagnostic examination.

6195. DOCTORAL COMPREHENSIVE EXAMINATION (1-0). Individual instruction, directed study, consultation, and comprehensive examination on a detailed prospectus of proposed dissertation research as well as an oral examination. Graded P/F/R only. Required of all doctoral students in the semester when they take the comprehensive examination. Prerequisite: BME 6194.

6197, 6297, 6397, 6697, 6997. RESEARCH IN BIOMEDICAL ENGINEERING. Individually approved research projects leading to a doctoral dissertation in the area of biomedical engineering. Graded P/F/R.

6395, 6695, 6995. INTERNSHIP IN BIOMEDICAL ENGINEERING. Students are placed with a biomedical engineering company or a hospital to gain firsthand industrial or clinical engineering experience. The company or hospital assigns projects, and a faculty member monitors the student's progress. Students register for 3 (BME 6395), 6 (BME 6695), or 9 (BME 6995) credit hours during each semester. Prerequisite: completion of at least 9 graduate credit hours in BME and good standing in the graduate program.

6399, 6699, 6999. DISSERTATION. Preparation and submission of a doctoral dissertation in an area of biomedical engineering. 6399 and 6699 graded R/F only; 6999 graded P/F/R. Prerequisite: admission to candidacy for the Ph.D. in Biomedical Engineering.

Courses offered at The University of Texas Southwestern Medical Center at Dallas (U.T. Southwestern):

BME 5300D. Special Topics in Biomedical Engineering
BME 5396D. Individual Laboratory Projects
BME 5363D. Digital Processing of Medical Images
BME 5306D. Biochemistry
BME 5307D. Human Anatomy Lectures
BME 5308D. Human Anatomy Laboratory
BME 5309D. Human Physiology
BME 5331D. Introduction to Orthopedic Mechanics
BME 5332D. Orthopedic Biomaterials.
BME 5680D. Mammalian Physiology

Combined Degree Plan: Bachelor of Science in Biology and Master of Science in Biomedical Engineering

This five-year curriculum prepares students for careers in the fast growing biotechnology and biomedical engineering industries. The curriculum also prepares students for medical school and advanced study. Students are required to take courses from engineering, life sciences and liberal arts, culminating in a five-year Master of Science Degree in Biomedical Engineering, including a Bachelor of Science Degree in Biology. The curriculum is offered jointly by the College of Engineering and the College of Science.

Description

Biomedical engineers use quantitative methods and innovation to analyze and to solve problems in biology and medicine. Students choose the biomedical engineering field to serve people, to partake in the challenge and excitement of working with living systems, and to apply advanced technology to complex problems of medical care. Through this program, students learn the essentials of life science, engineering theory, and the analytical and practical tools that enable them to be successful in the biotechnology and biomedical engineering industries. The program includes coursework in the basic sciences, core engineering, biomedical engineering, and advanced biotechnology disciplines. Both didactic classroom lectures and hands-on laboratory experience are emphasized. Additionally, students are required to take general educational courses in literature, fine arts, history, political science, and social science.

Career Opportunities

The program prepares students as biomedical engineers for careers in industry, in hospitals, in research facilities of educational and medical institutions, and in government regulatory agencies. It also provides a solid foundation for those wishing to continue for advanced degrees. For those planning to pursue a medical degree, this cross-disciplinary curriculum offers a solid foundation in engineering, which is an advantage in preparing for a medical career.

See the U.T. Arlington Undergraduate Catalog for a more detailed description of this program.

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